A proof of the unity, integrity and autopoietic autonomy of the whole human genome

  • Jean-claude PEREZ


Global analysis of 3 human genomes of increasing levels of evolution (Neanderthal / Sapiens Build34 / Sapiens hg38) reveals 2 levels of numerical constraints controlling, structuring and optimizing these genome's DNA sequences. A global constraint - called "HGO" for "Human Genome Optimum" - optimizes the genome at its global scale. The same operator applied to each of the 24 individual chromosomes reveals a hierarchical structure of these 24 chromosomes. Then analysing the single strand DNA CG / TA proportions at whole chromosomes and genome scale reveals strong fine-tuned numerical ratios evidencing the "closure" nature (Varela's autopoiesis theory) of whole human genome.


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How to Cite
PEREZ, Jean-claude. A proof of the unity, integrity and autopoietic autonomy of the whole human genome. Research in Biological Chemistry, [S.l.], v. 1, n. 1, p. 1-10, nov. 2017. Available at: <https://rbchemistry.com/index.php/rbc/article/view/2>. Date accessed: 14 dec. 2018.

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